📗 Even when its origins are still uncertain, the uses of calendula as a medicine and as a colouring were known to the old herbalists, especially Arabs and Hindus. Greeks, who started cultivating it more recently, used calendula flowers to decorate their feasts and to make garlands to honour their heroes. Calendula has long been used in topical applications, to treat skin ulcers, infected wounds, diaper rash, eczema, varicose veins, hemorrhoids, periodontitis and conjunctivitis. The study revealed that Calendula oil has great potential to be used for pharmaceuticals purposes. Natural oil derived from calendula plant has good results when used in cosmetics. Antioxidant activity, anti-tumor promoting effect, wound healing and anti-carcinogenic effect is the main reason of using calendula oil in medicines and cosmetics. Calendula oil has high moisturizing effects.