📖 This book aims at publishing research carried out by author on synthesis of a scaffold chalcone and its further use as anti-malarial, antifilarial and antimicrobial agent. The scaffold was further used to prepare flavones and their NO inhibitory activity was examined. DNA binding studies were also carried out as the molecule contained intra charge transfer actvity, This book will allow readers to develop interest in synthesis of small molecules with multifarioius actvity.