📓 Sulfonamide derivatives are well known due to their therapeutic activities. In the present research work new sulfonamide derivatives have been synthesized by the condensation of amines and benzenesulfonyl chloride molecules. Aqueous media was used for the synthesis of targeted molecules since it is environment friendly, cheaper and give good purity and yield. The synthesized molecules were characterized using IR, element analysis technique and single crystal X-Ray diffraction studies.